Technology Networks

Two New Studies Show Gallium-Containing Compounds Increase Bone Strength in Osteoporosis
Extended treatment with the active ingredient significantly increased bone volume and calcium content in animals with induced osteoporosis.

NitricBio Selects Clinipace Worldwide to Manage Multiple Clinical Trials
Clinipace will manage and deploy multiple studies in support of medical applications of topical nitric oxide gas.

Altea and KAI Enter into a Preclinical and Clinical Development Agreement
Agreement aims at the delivery of certain KAI compounds using Altea’s transdermal delivery technology.

Reseach papers on Selective Androgen Receptor Modulator​​​​s (SARMs)

SARMs work by stimulating androgen receptors specifically in muscle and bone cells and assisting with muscle and also bone growth, while having low effects on the other cells in the human body (unlike regular steroids which place high stress on human cells). They have a special affinity for certain tissues like muscle and bone, but not for others, like the prostate, liver, and also the brain. This means that a more rapid muscle and bone growth can be gained without unwanted growth in other parts of your body.

Sarms UK also said in some clinical trails that SARMs also don’t break down into unwanted molecules that can cause serious side effects, like DHT and estrogen in men as easily as anabolic steroids do. Also, because SARMs can be less powerful than regular steroids, they don’t suppress natural testosterone production as heavily as some steroids, making them easier to recover from and rarely requiring any post-cycle therapy (PCT).


Synthesis and trafficking of the tonoplast potassium channel AtTPK1
(1) Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milan, Italy (2) Institut fur Biochemie und Biologie, Universitaet Potsdam, Potsdam-Golm, Germany

Sorting signals of tonoplast proteins and the pathway they follow through the endomembrane system are still poorly characterized. Using Brefeldin A (an inhibitor of the Golgi-mediated traffic) we showed that a Golgi-dependent pathway for tonoplast delivery may exist. Then we generated various chimeric TPK1-TPK4 fusions, exchanging various domains. We observed that the cytosolic, C-terminal domain of TPK1 is sufficient to re-direct the plasma membrane TPK4 to the tonoplast.

Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy

The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.


Peptide Studies on BPC-157 for stomach ulcers, intestinal damage and inflammatory disorders 

A team of young researchers from the company at Peptides.net have recently conducted rodent trail studies on the BPC-157 peptide that shown it has protective effects not only on the stomach but extending beyond and into the intestinal tract. BPC-157 has also been shown to benefit stomach ulcers , intestinal damage such as fistulas and some inflammatory disorders, and can also have benefits on bone and joint healing and growth rates, as well as organ damage. It’s also shown some influences on the brain. Researchers have observed marked protective effects when BPC-157 is administered to rats alongside a research toxin or damaging surgical procedure.


Marketing Communications Specialist Position in San Jose, CA
Thermo Fisher Scientific
This position, based in San Jose, CA within the SID Division, will manage promotion of Thermo Scientific mass spectrometry products and services.

 

St. Jude Children's Research Hospital has an opening for a Senior Research Technologist (Job Number 18046)
St Judes Research Hospital
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment.

Postdoctoral Associate Microfluidics
Virginia Bioinformatics Institute
Blacksburg, VA, United States of America

World Drug Delivery and Formulation 2010 - Dusseldorf, Germany
26 January 2010 - 27 January 2010

Radisson BLU Scandinavia Hotel, Dusseldorf, Germany

World Drug Delivery and Formulation 2010 is the event this year for both scientific and business leaders working in formulation and delivery to debate the challenges affecting them.

This multi stream delivery and formulation event will focus on both scientific and business issues. This will give everyone the perfect opportunity to attend sessions dedicated to their main area

2010 Biomanufacturing Summit, San Diego, California
26 January 2010 - 27 January 2010

The 2010 Biomanufacturing Summit will uncover tomorrow’s strategies to help you streamline processes, enhance capacity, reduce costs and break through the downstream bottleneck. Join us at this premier conference and networking event designed specifically for senior executives in manufacturing, process development and product operations.

PITTCON Conference & Exposition 2010, Orlando, Florida
28 February 2010 - 05 March 2010

Pittcon 2010, the world’s largest annual conference and exposition for laboratory science. Pittcon offers the latest innovations from nearly 1,000 exhibitors, unique networking opportunities with world renowned scientists and exceptional educational opportunities.
  


Freedom from filters! The Biochrom Asys UVM340 Microplate Reader more>>>


Personal Solvent Evaporator Offers Optimised Storage Method more>>>


Affordable, High Quality 2ml Compound Storage Plate more>>>


Compact Freeze dryers provide greater capacity & improved controls … more>>>


Screening for Transient Drugs/Fragments: New Opportunities for Drug Discovery

Sten Ohlson, Professor, University of Kalmar, speaking at MedChem Europe 2009

Cleaning Microreactors
Syrris Ltd

This application note gives hints and tips on cleaning & unblocking flow reactors, i.e. chips or tube based reactors. It is suggested that the whole document is read before attempting to unblock a reactor.