deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis
Findings offer promising target for drugs to better regulate calcium metabolism, are integrated into deCODEme™.

deCODE-led Mega-study Finds new Genetic Clues to Causes of Schizophrenia
Findings expand knowledge of the biology of the disease and provide potential new drug targets.

Fate Therapeutics Granted Exclusive License to Stem Cell Modulators for Osteo-Regeneration
The intellectual property rights covers small molecule compositions and methods for inducing bone formation granted by The Regents of the University of California.

Drug Discovery Unit, University of Dundee, and DNDi Collaborate to Identify Drug Candidates to Treat Visceral Leishmaniasis
The £1.8m collaboration focuses on the discovery and development of affordable and effective therapies for the disease.

Engineering Innovative Solutions for 21st Century Medicine
EPSRC announced £41M funding for four new UK Centres of Excellence in Medical Engineering.

Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy

The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.

Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy

The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.

Senior Director ADME
The RSA Group
Hatfield, Herts, UK

Mass Spectometry Scientist
Roswell Park Cancer Institute
Buffalo, NY, USA

Principal HTS Scientist
St. Jude Childrens Research Hospital
Memphis, TN, USA


Target Discovery World Congress, South San Francisco, CA, USA
04 August 2009 - 05 August 2009

Target Discovery World Congress will be a meeting focusing on the research looking to find new potential drugs for development. The topics will include presentations on the latest in screening platforms and new methods such as those in High Content and Label-Free Screening and will also focus on the work being done looking for new drug targets in some of the major protein families including Ion Channels, GPCRs, Protein Kinases, Nuclear Receptors and the Ubiquitin Pathway.

Drug Delivery, London, England
02 September 2009 - 02 September 2009

The summit includes three one-day symposia on the following subjects: Delivery of Small Molecules & Nucleic Acids, Delivery of Macromolecules and Formulation & Solubility

Second International Symposium on Combinatorial Sciences, Beijing, China
19 September 2009 - 22 September 2009

The Second International Symposium on Combinatorial Sciences in Biology, Chemistry, Catalysts and Materials (SCS-09) will feature plenary lectures from: Jim Wells, University of California, San Francisco ;Jon Ellman, University of California, Berkeley; Dennis Curran, University of Pittsburgh, U.S.A.
  


Retigabine and Therapeutic Indications of Activating Neuronal KCNQ Voltage-Gated Potassium Ion Channels

Jim Wu, Head of Discovery Biology, Roche R&D Center, speaking at Ion Channel Targets 2008

Cleaning Microreactors
Syrris Ltd

This application note gives hints and tips on cleaning & unblocking flow reactors, i.e. chips or tube based reactors. It is suggested that the whole document is read before attempting to unblock a reactor.