Multicomponent Reactions: New Synthetic Opportunities for Privileged Heterocyclic Cores
Rodolfo Lavilla, Professor of Chemistry and Molecular Pharmacology
Date Posted: Wednesday, December 19, 2007
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About the speaker
Post-Doctoral Fellow. Department of Chemistry and Biochemistry. University of California, San Diego. (Advisor Prof. E. Wenkert). 1988-1990.
Ph. D. University of Barcelona 1987. Advisor Prof. M. Alvarez.
M.Sc. University of Barcelona. 1983.
B. Sc. University of Barcelona.1982.
Profesor. Organic Chemistry. Faculty of Pharmacy.
University of Barcelona. (1991- )
Advisor of 5 Ph. D. thesis and over 20 Master thesis.
“Natural Products Synthesis”. (Indole Alkaloids,)
“Heterocyclic Chemistry. New Reactivity of Azine derivatives”
“Multicomponent Reactions based on Pyridine derivatives”
“Synthesis of scaffolds for lead finding” (in collaboration with pharmaceutical companies)
Over 45 papers in the fields of heterocyclic chemistry, multicomponent reactions and natural product synthesis.
New synthetic protocols arise from the use of fundamental O- and N-heterocycles as the key reagents in multicomponent reactions. The participation of cyclic enol-ethers, dihydropyridines and (benzo-fused)azines in these processes lead, in a straightforward manner, to a diverse set of complex drug-like compounds.