Analytical Sample Transport – A Pneumatic Solution

Matthew Cook, Bob Lawson and Paul Martin, TTP Labtech

Date Posted: Friday, February 02, 2007

Print Email to a friend

Pneumatic air transport systems can provide a safe, efficient and rapid means of sending samples within different departments of a research laboratory.

These systems are often used within a hospital, supermarket or bank and represent an effective method for sending samples or packages to different departments

TTP LabTech has used this technology for over 6 years, predominately in our comPILER and comPOUND systems

Recently, the technology has been applied to an automated chemistry synthesis project. All compounds produced during synthesis are analysed during and after processing using a variety of different methods.

TTP LabTech’s transport system sends sample ‘vials’ from a central hub directly to the sample collection device, then to the analytical hardware and finally to a storage rack or waste collection point.

Click here to open poster PDF

Comments about this Poster

Click Here to Leave a Comment about this Poster

Related Posters

Use of Nanolitre Pipetting in Hit-to-Lead Optimisation
, ,
Assay-ready plates are becoming key to maximizing throughput for many HTS departments. These plates contain test compounds prepared from library stocks ahead of time at the correct concentrations. DMSO is routinely used for compound dissolution, but its presence at concentrations above 1% can markedly affect assay performance. Thus, accurate nanolitre quantities of DMSO-based stock solution are required to keep concentrations low when preparing assay-ready plates.

High Throughput High Content Screening using a Multiwavelength Microplate Cytometer
, ,
The Acumen eX3, a multiwavelength microplate cytometer, offers 405, 488 and 633 nm laser excitations in one instrument. This advancement significantly extends the range of fluorescent reagents that can be combined in multicolour, multiplexed assays over a wavelength range for excitation that is similar to that of white light source instrumentation. Thus, it permits seamless transfer of high content assay protocols, developed using CCD-based imaging devices, onto the Acumen eX3 for screening.

Utility of 405nm-Excitable Dyes in High Content Screening Using an Acumen Explorer Microplate Cytometer
, ,
In this study, we have used an Acumen Explorer equipped with a violet 405nm laser in conjunction with a selection of shorter-wavelength amine-reactive fluorophores (Invitrogen, Molecular Probes) to demonstrate a greater utility for blue fluorescent probes within high content assays.

A Total Solution to Provide High Content Primary and Secondary Screening of a Compound Library
, ,
TTP LabTech recently published a novel approach using the Acumen Explorer with Invitrogen’s GeneBLAzer technology to measure GPCR activation in cell-based assays. This is multiplexed with a cytotoxicity readout to reduce false positives commonly identified in bulk fluorescence assays. TTP LabTech and Velocity11 have designed a fully automated, single platform using this assay to perform both primary and hit-confirmation screens on a 400,000 compound library in only one week.