Achieving Ultra High Performance Screening
David James Morris, Steve Mayhew and William Hoyland,
IDBSDate Posted: Wednesday, January 10, 2007
High throughput (HT) and Ultra High Throughput (UHT) screening remains a valuable and necessary approach to modern drug discovery. With the use of numerous standardized biochemical assays now commonplace, successful application of HTS requires accurate and meaningful handling of the experimental results. Specifically, this means capturing vast data volumes generated by HTS and UHTS programmes and subsequent validation and verification. Decision making regarding HTS data can be supported via comprehensive and intuitive visualization of results. Also important is the establishment and maintenance of analysis templates for this type of experiment. In order for HTS and UHTS to be successfully implemented in drug discovery, all the aforementioned issues must be addressed.
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