Aug
15 - Call For Papers 2nd Russian Symposium
A call for papers has been issued by the 2nd
Russian Symposium and Practical Workshop entitled Modern Technologies
In Combinatorial Chemistry. This is to take place between 29th
and the 31st October, 2001 at Chemistry Department of Moscow State
University, Moscow, Russia. It is being jointly organised by the
Chemistry Department of Moscow State University and the Russian
Mendeleev Chemical Society (Section of Medicinal Chemistry).
Key
Topics so far include: Review lectures on practical aspects of
high-throughput synthesis, Overview of basic equipment and technique
for combinatorial chemistry and parallel synthesis, Invited lectures
of industrial scientists experienced in the use of such equipment
and technique and a Practical workshop on solid-phase combinatorial
synthesis.
For further information email:
confer@org.chem.msu.su 
Aug
15 - Exelixis agreement with Elan
Exelixis, Inc. has entered into an agreement
with Elan Pharmaceuticals, Inc., a subsidiary of Elan Corporation,
plc to produce a custom high-throughput screening compound library
for use by both parties. Under the terms of the three-year agreement,
Exelixis will use its combinatorial chemistry platform to generate
a large, small molecule library for high throughput screening.
Elan Pharmaceuticals will pay Exelixis an initial upfront fee
as well as ongoing compensation as compounds are delivered. Both
parties have the ability to use the compounds resulting from this
collaboration for internal drug discovery and collaborative efforts.
Exelixis
President and CEO said, "This is our first chemistry-focused
collaboration" and " it {the agreement} offsets some
of the cost of building our large high throughput screening compound
library for drug discovery at Exelixis." Exelixis currently
generates novel, genetically and biologically validated targets
through its expertise in model system genetics.
For further information:
www.exelixis.com 
Aug
14 - KXEN announce partnership with FOVEA
KXEN announce a partnership with FOVEA, a software
distributor located in Switzerland. KXEN offers a suite of predictive
and descriptive modeling engines based upon Vapnik's theory of
mathematics for scoring, classification, clustering, and variables
contribution, to transform data into knowledge. KXEN partners
with systems integrators and original equipment manufacturers
to integrate its analytic software into their applications.
For further information:
www.kxen.com 
Aug
14 - BioWisdom announce integration of Abcam's antibody catalogue
BioWisdom are announce the completion of the
integration and alignment process of Abcam's branded antibody
catalogue into Discovery Portfolio. Discovery Portfolio is a customisable
drug discovery target tracking system, with an integrated view
of both public and proprietary content associated with targets.
Users of Discovery Portfolio will now be able to identify the
availability of Abcam branded antibodies, and to receive alerts
to changes in the antibody catalogue and any new antibodies, which
become available and relate to their specialised research interests.
For further information:
www.biowisdom.com
www.abcam.com 
Aug
9 - Graffinity announces alliance with Biosearch Italia
Graffinity Pharmaceutical Design GmbH announced
a drug discovery alliance with Biosearch Italia SpA. Under the
agreement, Biosearch Italia will use Graffinity's drug discovery
technology to identify high quality compounds against innovative
targets identified by Biosearch Italia . This agreement expands
Biosearch Italia's capability of developing novel antibiotics
active against multi-resistant microorganisms. Financial terms
were not disclosed.
For further information:
www.graffinity.com 
Aug
8 - $1,111,000 USD on offer at InnoCentive
A new website designed to offer financial award
for the "best" solution to a unique scientific problem.
The InnoCentive is a unique scientific problem, that is posted
by solution Seekers looking to find the "best" solution
for their problem. If a solution is judged the "best",
the Solver receives a financial award, which varies per InnoCentive.
The solver is what they call the person (probably a scientist)
who submits an answer(s) to posted InnoCentive(s). This person
must register, sign an agreement, and be capable of transferring
ownership.
InnoCentive
was founded by Eli Lilly and Company, however InnoCentive is currently
working with several other world-class, research-driven corporations
who will be adding scientific challenges to the InnoCentive site
in the coming months. There are conditions and solvers must have
the ability to transfer ownership of intellectual property to
the Seeker company and importantly if you use your employer's
facilities to create your submission, you must have your employer
sign the solver agreement.
For further information:
www.innocentive.com 
Aug
7 - Pharmacopeia launch redesigned web site
Pharmacopeia announce the launch of its newly
redesigned corporate and drug discovery web site. The site features
corporate news, investor information, career development opportunities
and new programs and capabilities for drug discovery. Descriptions
of opportunities in Lead Discovery, Lead Optimisation and Collaborative
Drug Discovery are detailed in the Drug Discovery section of the
site.
For further information:
www.pharmacopeia.com 
Aug
3 - Web Exclusive for CombiChem.net
CombiChem is pleased to publish the complete abstracts from EuroCombi
- 1, the First Symposium of the European Society for the Combinatorial
Sciences, exclusively on the Internet.This includes the abstracts
from the Keynote Lectures, as well as the invited lectures (11),
the Lectures (46) and all the Posters (78). If you missed this
very successful meeting, visit the new section of the site to
catch up!!
To visit the new section:
CLICK
HERE  
Aug
3 - Pharmacia Establishes Biovitrum AB
Pharmacia Corporation announced that it has
completed an agreement with a group of outside investors to establish
Biovitrum AB, a new, Swedish -based biotechnology company. Biovitrum
will consist of Pharmacia's Swedish -based metabolic disease research
group, its related biopharmaceutical development unit, and its
blood fractionation business.
Pharmacia
will own approximately one-third of Biovitrum and may, over time,
further reduce its ownership position as additional outside investors
have the opportunity to participate in the new venture.
For further information:
www.pnu.com 
Aug
2 -GlaxoSmithKline divests Affymax
GlaxoSmithKline plc announced an agreement
for the sale of the Affymax business, a GSK drug-discovery operation
in California, to Affymax Inc. a new company founded by a syndicate
of venture capital firms. Glaxo Wellcome originally purchased
the Affymax business as a technology-development centre, focused
on combinatorial chemistry and high-throughput screening.
The
Affymax business technologies, will continue to be used in the
GSK R&D organisation.Under the terms of the divestiture, subject
to a definitive agreement, GSK will receive non-voting preferred
stock in Affymax Inc. in exchange for the Affymax business. GSK
will not participate in the management of Affymax Inc, nor have
any representation on the Board.
For further information:
www.gsk.com 
Aug
1 - Bharavi Laboratories increase Product line
Bharavi Laboratories introduce novel tartaric
acid linked PS-DVB resins, namely, diacetyl-L-tartaric acid (DATA),
L-tartaric acid methyl ester (TAME) and L tartaric acid (TAR)
bound to aminomethyl PS-DVB. These resins are useful for chiral
separations as well as templates for asymmetric induction (e.g.,
Sharpless epoxidation)
For further information:
www.bharavilabs.com 
Jul
30 - Update of Library of Rare Chemicals
Sigma-Aldrich have issued an update disc of the new version of
their Library of Rare Chemicals. The library contains over 90,000
research samples acquired from academic scientists. Each item
contains a structure, molecular formula, molecular weight and
the unique Sigma-Aldrich catalogue number.
For further information:
www.sigma-aldrich.com 
Jul
30 - ChiraSource2001 Announced
The Catalyst Group Resources announce ChiraSource2001
- "The Dynamics of Speed to Market Through Process Innovation"
- Sixth Annual Conference & Exhibition to be held on the 12
- 14th November, 2001 in Philadelphia, Pennsylvania, USA. In addition
to the issues of chirality, ChiraSource2001 will feature new areas
including "Software and Intranet Services", "SMB
Separation Implementation" and "Organization Management
Tools" available to speed-up the time-to-market, from discovery
to launch.
Conference
highlights include the Keynote Address by Mr. James Mack, CEO
of Cambrex Corporation, Avecia's presentation on "Powerful
New Technologies for Chiral Molecules", as well as presentations
by GlaxoSmithkline, Bristol-Myers Squibb, Pfizer Inc., Abbott
Laboratories, and Schering Plough Research Institute. Advanced
Separation Technologies (ASTEC) and Medichem Research will provide
insight into the latest developments in SMB Separation Implementation.
For further information:
www.catalystgrp.com 
Jul
26 - Viaken and InforSense Partnership
Viaken Systems Inc and InforSense announced
that they are developing a marketing and distribution partnership
for the Kensington data mining and visualization suite in the
life science domain. The Kensington suite will be offered by Viaken
as part of its set of hosted solutions and professional services
products.
Kensington
is an Internet-based knowledge management platform for the analysis
of life science research data, supporting automated discovery
and collaborative research. The system combines data mining and
analytical functions, visualization tools, collaborative work
support, and intellectual property management functions within
an integrated, extensible, and scalable framework.
For further information:
www.inforsense.com
www.viaken.com 
Jul
25 - Platform Computing Open Source's Programs
Platform Computing Inc. announced that it is
contributing two open-source programs to run computationally intensive
algorithms in the life sciences field. By open sourcing the programs,
scientists will be able to customize applications to get the benefits
of Platform's LSF ActiveCluster. Platform's contribution of open
source programs for the applications Blast and HMMer will enable
faster completion times for jobs as LSF ActiveCluster will split
jobs into smaller pieces that can run in parallel.
For
further information:
www.platform.com 
Jul
24 - LION bioscience and Platform Cooperation
Platform Computing Inc. announced that LSF ActiveCluster now supports
LION bioscience SRS. The integration of LSF ActiveCluster and
SRS will enable LION bioscience customers to harness corporate
desktops to accelerate the overall drug discovery process.
SRS
is a data integration platform that provides access to biological
and life science data stored in more than 400 internal and public
domain databases and enables the queries through one interface.
Platform's LSF product line distributes computing jobs to servers
and workstations, while LSF ActiveCluster extends that capability
to corporate PCs.
For further information:
www.lionbioscience.com
www.platform.com 
Jul
23 - Gilson and Avantium Technologies collaboration
Gilson, Inc. and Avantium Technologies, Inc.
have entered into a development program to add enhanced software
features to Gilson's line of Lab Automation robotic products including
the 215, Constellation, and Cyberlab product families. The enhanced
software will utilize certain aspects of Avantium Technologies'
VirtualLab software suite and the Gilson 735 Instrument Control
Software.
The
enhanced product will provide an advanced graphical user interface,
simple set-up wizards, informatics, scheduling tools, protocol
management, visualization tools and ease of integration capability.
These features will allow maximisation of the data flow in the
lab between chemists, equipment, and data warehouses.
For further information:
www.gilson.com
www.avantium.com 
Jul
23 - Signature Acquires Cambridge Discovery Chemistry, Inc.
Signature BioScience, Inc. announced that it
has acquired 100 percent of the stock of Cambridge Discovery Chemistry,
Inc., a chemistry operation owned by Millennium Pharmaceuticals,
Inc.. Signature has signalled its intent to acquire key elements
for building an integrated discovery platform, to enable the company
to roll out its parallel target and compound selection process,
WaveScreen, aimed at the rapid discovery of new lead compounds.
With the acquisition, Signature gains 26 people, principally chemists,
a number of key corporate collaborations and a state-of the-art
chemistry laboratory.
Millennium
acquired CDC in July 2000 as part of its acquisition of Cambridge
Discovery Chemistry Limited, a UK-based company that operated
CDC as its US based subsidiary. Cambridge Discovery Chemistry
Limited was renamed as Millennium Pharmaceuticals Limited, and
continues to operate in the UK as a wholly owned subsidiary of
Millennium Pharmaceuticals, Inc.
For further information:
www.signaturebioscience.com
 
Jul
19 - Adaptive Screening Ltd Launched
Imperial College Innovations announces its
latest spin out, Adaptive Screening Ltd (ASL). Formed in collaboration
with The Generics Group and the University of Glasgow, the company
offers a new approach - known as Adaptive Screening - to identifying
and rationalising potential drug candidates.
Adaptive
Screening presents the pharmaceutical industry with an alternative
approach to high throughput screening methods based on patented
core technology platforms: Adaptive Arrays, Cellular Arrays, Lead
Hunter and Adaptive Screening Environment - which have stemmed
from research carried out at Imperial, Glasgow and Generics.
For further information:
www.adaptive-screening.com
 
Jul
18 - ChemNavigator offers new services
ChemNavigator now offers library design services, including information-biased
library design and diversity selection, specific to project needs.
If you need small-molecule compounds that are specific to a biological
target, known patents, toxicological profiles, or other scientific
information ChemNavigator uses a proprietary cheminformatics system
to identify commercially accessible compounds that are specific
to your area of research, relates scientific information relevant
to these compounds, and keeps the information up-to-date.
For further information:
www.chemnavigator.com
 
Jul
16 - PerkinElmer agrees to acquire Packard BioScience
PerkinElmer, Inc. and Packard BioScience jointly
announced a definitive agreement for PerkinElmer to acquire Packard
BioScience in a deal valued at approximately $650 million, including
net indebtedness. The transaction, which is subject to customary
closing conditions and regulatory approvals, as well as the approval
of the shareholders of both PerkinElmer and Packard BioScience,
is expected to close during the fourth quarter.
In
a statement Gregory L. Summe, Chairman and CEO of PerkinElmer
said that Packard BioScience represents an excellent strategic
fit as a leading supplier of automated liquid handling, sample
preparation tools and advanced biochip technologies. Liquid handling
is a critical, enabling step in both proteomics and genomics workflow,
and increases the productivity of our customers' drug discovery
processes. Packard BioScience's core capabilities in this area,
its complementary range of products, its impressive new product
development pipeline, and its well-respected team of field sales
and service experts will enable us to provide more powerful solutions
to our expanding base of life sciences customers.
For further information:
www.perkinelmer.com
 
Jul
16 - Tularik Acquires CAMD from Protherics
Protherics PLC announced the sale of its Computer
Aided Molecular Design ("CAMD") operations to Tularik
Inc., for 400,000 Tularik shares with a current value of approximately
US $9.4 million. The sale will include the transfer of Protherics'
CAMD technology consisting of its Prometheus virtual screening
software and its VA Linux hardware system.
Existing
CAMD research agreements will also transfer to Tularik. Dr. J.
A. Miller will be transferring to Tularik with the CAMD business
and consequently has resigned as a director of Protherics. As
a result CAMD will focus on realising the value of their technology
on Tularik projects.
For further information:
www.tularik.com
 
Jul
13 - Events Archive Created
Due to numerous requests from scientists wanting
to follow up on past conferences and symposia a New section of
the site has been created. The 'Events Archive' is now open giving
access to a listing of past events that had been listed in our
comprehensive Events Index.
For further information:
Events
Archive  
Jul
10 - Eurocombi -1 a great success
The first symposium organised by the European
Society for Combinatorial Sciences was held last week in Budapest.
Over 340 delegates listened to 60 presentations on the latest
techniques and advances in this industry. In additon, 80 posters
were presented and 37 exhibitors displayed the latest products
and services on the market. A number of awards were presented
for various oral presentation categories and best poster. The
next symposium will be held in Copenhagen in 2003 .
For further information:
www.eurocombi.com 
Jul
9 - Call for poster papers Combinatorial Chemistry
A call for poster papers has been issued for
the conference "Combinatorial Chemistry: Applying the Technology".
All papers submitted will be undergo a review process. Submission
of a poster therefore does not guarantee acceptance. The deadline
for abstracts is Friday, July 20, 2001.
Submitted
poster papers must be accompanied by a 150-word abstract on a
standard American Chemical Society Abstract Form, which is available
on the Internet. Abstracts can then be submitted by E-mail as
an attachment.
For abstract form see:
www.acs.org
and email
abstracts to:
ACSProSpectives@acs.org 
Jul
6 - BioFocus acquires Cambridge Drug Discovery
BioFocus has recently acquired Cambridge Drug Discovery. By augmenting
their existing medicinal chemistry technologies, BioFocus aims
to offer a wider range of integrated discovery services, including
assay development and HTS using new biology expertise from Cambridge
Drug Discovery.
For further information see:
www.biofocus.com 
Jul
5 - TimTec Corp announces expansion and Collaboration
TimTec Corporation has moved and expanded to
a new 30,000² foot facility with state-of-the-art synthetic
and analytical laboratories, cold storage rooms, weighing and
micro-plating labs, and larger receiving and shipping areas, co-located
with Empower Materials, Inc. of Newark, DE. TimTec and Empower
Materials have created a global partnership committed to the full
spectrum of custom synthesis, production, and support.
TimTec
Corporation provides chemical libraries for bioscreening, custom
synthesis, building blocks for combichem and reagents for organic
synthesis, database software, microplating, sample handling, weighing,
repackaging, labelling and quality control including NMR analysis.
Empower Materials, a subsidiary of Axess Corporation, manufactures
a family of amorphous thermoplastic polymers known as poly(alkylene
carbonates), tradenamed QPAC.
For further information:
www.timtec.net 
Jul
4- Chemical Inventory System with Direct Interface to Balances
ChemSW, Inc. announced a new capability for
the CIS Chemical Inventory System a built-in interface to the
complete line of Mettler Toledo balances. With this enhancement,
users can automatically add or subtract chemical amounts directly
from the balance, which saves time and improves the accuracy of
tracking inventory data on precious chemicals. The direct interface
also minimizes the number of keystrokes when subtracting or adding
amounts to a container. The balance interface capability is a
standard part of CIS Version 5 and is available as an upgrade
to users of earlier versions.
For further information:
www.chemsw.com 
Jul
3 - New appointments in ChemOvation expansion
ChemOvation Ltd has recruited two senior staff
members to the team. These appointments form a key part of the
company's current expansion. Keith Menear has joined as Head of
Chemistry. Dr Menear has a background in drug discovery, medicinal
chemistry and project leadership, gained from within a multinational
pharmaceutical company. He is now responsible for day-to-day operations
of organic chemistry and drug discovery. Xiao-Ling Cockcroft has
joined as Senior Modeller. Mrs Cockcroft is a computational modeller
who has undertaken drug discovery within large pharma and biotechnology
organisations. She is now responsible for leading the newly-expanded
compound modelling function within ChemOvation.
For further information:
www.chemovation.com 
Jul
2 - Agilent Technologies introduce APPI for Lc/Ms
Agilent Technologies Europe announced that
it will offer atmospheric pressure photoionization (APPI) on its
quadrupole and ion trap LC/MS systems. Agilent will offer the
PhotoMate Atmospheric Pressure Photoionization source from Syagen
Technology Inc. on Agilent's LC/MSD and LC/MSD Trap mass spectrometers.
The
PhotoMate source uses photons instead of electrons or solution
chemistry to initiate the ionisation process and can ionise compounds
that cannot be ionised using electrospray or APCI, or that are
poorly ionised using those techniques. A krypton lamp produces
photons at energy levels that ionise most analyte molecules while
minimizing the ionisation of common HPLC solvents. The result
is an ion source that complements traditional API techniques.
For further information:
www.agilent.com 
Jun
28 - Morphochem appoints Head of Business Developement
Morphochem AG, announced the appointment of
Dr Werner Schiebler as Head of Business Development. Dr Schiebler's
primary role will be to establish new strategic alliances for
Morphochem's with partners from the pharmaceutical and biotechnology
industry. In addition, Dr Schiebler will be intrinsically involved
in the formulation and generation of strategic options for Morphochem´s
internal small molecule drug discovery and development programs
with partnerships at various stages to develop Morphochem´s
product portfolio.
For further information:
www.morphochem.de
Jun 27 - Symyx Technologies
Announces Collaboration With Merck
Symyx Technologies announced an agreement with
Merck & Co. to develop a Discovery Tools System for the rapid
discovery, identification, and characterization of novel crystalline
salt and polymorphic forms of drug candidates. The methods, instruments,
and software included within the Polymorph Discovery Tools System
are used to identify the optimal crystalline salt and polymorphic
form of drug candidates to be formulated for use in clinical trials.
Under
the terms of the agreement, Merck will provide funding for Symyx'
Discovery Tools development effort and will purchase a Polymorph
Discovery Tools system upon completion and validation.
For further
information:
www.symyx.com 
Jun
26 - Complimentary Seminars on Integrated Data Management
Advanced Chemistry Development (ACD), Micromass and Nugenesis
Technologies are providing a series of complimentary seminars
entitled ' A Novel, Integrated Data Management System for Advancing
Drug Discovery and Development' . These will be held on July 16th
in London, UK , July 17th in Basel, Switzerland and on July 18th
in Berlin, Germany.
For further information
& Online Registration:
www.nugenesis.com 
Jun
25 - BioWisdom appoint Life Sciences Director
BioWisdom appoints Dr Julie Barnes as Director
of Life Sciences. Julie joins from GlaxoSmithKline to lead the
team of life science analysts, whose role is to position information
about public and proprietary drug discovery development resources
within the Discovery Portfolio platform.
For further information:
www.biowisdom.com 
Jun
25 - Cerep announces a drug discovery agreement with Aventis
Cerep announced a three year drug discovery
partnership with Aventis. Under the agreement, Aventis will utilize
on a non-exclusive basis Cerep's proprietary drug discovery platform
in its pre-clinical research process generating novel, advanced
candidates for drug development. On a fee-for-service basis, Cerep
will provide Aventis with access to its technologies in pharmacological
and pharmaceutical screening, to its profiling as well as to its
general pharmacology services for pre-clinical drug optimisation.
For further information:
www.cerep.fr 
|
|

CEM Introduces New Microwave-Enhanced
Synthesis Instrumentation
CEM introduces a new family of Focused Synthesis
Microwave-Enhanced Instrumentation. The Discover line of products
is a combination of CEM's Focused microwave technology into three
distinct platforms: an individual research system, automated sample
handling system and a fully integrated analysis system.
The
Discover line offers an option for converting traditional synthetic
methods to microwave methods, which claims to perform synthesis
reactions in minutes instead of hours, and increases yields whilst
reducing side reactions. CEM's Discover can accommodate a variety
of vessel sizes and shapes (from 1 to 125 mL capacity) and also
has variable speed stirring and a temperature and pressure feedback
system.
For further information see:
www.cemsynthesis.com 

Genevac introduces new
features for DD-4
Launched by Genevac for general use, the DD-4
is a general purpose centrifugal evaporation system. The DD-4
incorporates many of the features available in the higher performance
models such as the HT-4 Series II compact bench top, including
solid aluminium rotors and microtitre plates in swing rotors,
the capability to accommodate test tubes and vials in high capacity,
and temperature control and monitoring via an infra-red pyrometer,
known as RotorGuard. A number of optional Genevac features are
available, including: Dri-Pure anti-bumping System and HCl resistance,
along with a choice of pumps to suit specific applications and
solvent use.
For further information see:
www.genevac.com
 

New Sigma - Aldrich Combinatorial
Chemistry Catalogue
September sees the 2001 Sigma-Aldrich Combinatorial
Chemistry Catalogue launched. The catalogue claims to offer "a
One-Stop-Shop for all your CombiChem needs". The handbook
includes over 600 resins from Aldrich and Fluka along with glassware
and equipment items from Sigma, Aldrich and Supelco. Visit the
Sigma-Aldrich web site to register for your copy.
For further information see:
www.sigma-aldrich.com 

Software enhancement delivers
MSDS Data Via Web
ChemSW, Inc. announces MSDS SimpleView Web
an extension of the Oracle version of the company's MSDS (Material
Safety Data Sheet) Digital Filing Cabinet software program. The
new version further automates MSDS management by providing access
via the web on corporate intranets. The program helps companies
meet OSHA requirements on the availability of chemical safety
information and eliminates on-site storage of paper files.
For further information see:
www.chemsw.com 

JCL MiniHolder for LC
Jones Chromatography launch the JCL MiniHolder
for 50mm Id preparative LC. It is a compact, bench mounted, axial
compression unit utilising the back pressure generated by the
LC pump to operate the axial compression jack. A range of high
performance, pre packed, 50mm Id cartridges accompanies the holder.
These may be packed with 7u Genesis Prep, 8u Apex Prepsil or other
quality packings.
For further information see:
www.jones-chrom.co.uk 

Biotage Introduces New HPFC
FLASH 40 System
Biotage, Inc announced the introduction of
the FLASH 40+ system. The FLASH 40+ compression module has been
improved with a quick-release design and the system includes a
FLASH+ stand with multi-position collection arm and new stand-alone
compression module. FLASH 40+ cartridges can purify up to five
grams of sample and are designed for complex mixtures from 100-milligrams
to two grams.
The
FLASH 40+ compression module reduces solvent consumption, increases
purity and reduces handling when compared to glass columns. Samplet
technology provides the ability to pre-absorb up to 15 mL of reaction
mixture in one step and enhances separation performance.
For further information see:
www.biotage.com 

LeadScope Announces the Release
of ToxScope
LeadScope, Inc., in collaboration with ddplatform LLC, introduces
ToxScope, a series of toxicity databases. ToxScope correlates
toxicity information with structural features of chemical libraries,
and creates a data mining system that incorporates the searching
and browsing capabilities of LeadScope EnterpriseT Server. The
ToxScope databases encompass acute toxicity, hepatotoxicity, mutagenicity
and carcinogenicity and enables the user to make side-by side
comparisons of efficacy screening and toxicity information.
Available
with ToxScope are consulting services with ddplatform LLC and
LeadScope for data mining of the customer's internal toxicity
data.
For further information see:
www.leadscope.com 

Platform Computing Corporation
launch LSF ActiveCluster
Platform Computing Corporation announced the
launch of software that allows enterprises to harness the unused
processing power of their desktop computers. The computational
power of most PCs is wasted approximately 90 percent of the time,
so tapping into this resource lets enterprises realize a significant
jump in processing power with no additional hardware investment.
LSF ActiveCluster extends Platform's core Load Sharing Facility
(LSF) product line, which distributes computing jobs to servers
and workstations.
Companies
with computationally intense problems, such as gene sequencing
and drug design or high throughput testing, have traditionally
run simulations on supercomputers or clusters of dedicated Unix/Linux/NT
workstations. LSF ActiveCluster, a complementary technology, allows
enterprises to extend their processing reach by taking advantage
of unused desktop cycles. When a PC is idle or underutilized,
it contacts the LSF ActiveCluster server, which dispatches a suitable
distributed computing job. Once the desktop completes the task,
it returns results to the server and is assigned a new task. The
LSF ActiveCluster client runs as a continuous background process,
so the PC user sees no decrease in performance.
For further information see:
www.platform.com 

Metz Reaction Station Large Volume Parallel
Synthesis
The Metz 6 Position Reaction Station offers parallel synthesis
with refluxing in 150ml reaction vessels. Supplied with a set
of glassware for parallel synthesis and refluxing, the Metz offers
microprocessor controlled magnetic stirring from 400rpm to 2000rpm
and a temperature range of ambient +5°C to 150°C. For
inert chemical reactions, the glass assembly allows argon or nitrogen
to be simultaneuously passed across all 6 reaction positions.
The Metz 6 Position Unit is one of a range of Metz Reaction Stations,
including 10, 25 and 50 Position models, Cooling models and systems
designed for robotic integration.
For further information see:
www.radleys.com
 

Radleys Discovery Technologies
launches new Web Site
Radleys Discovery Technologies (RDT), which
specialises in the development of practical systems for parallel
and combinatorial chemistry, has launched a new web site designed
to provide product and application advice. Radleys.com offers
a easy way to access product details and contains technical and
application information.
The product section covers the full range of RDT
products, including the Carousel Reaction Station and more recent
developments such as the Stacker Parallel Purification, also contains
details about the range of accessories and consumables. The Technical
section, which will be regularly updated, includes scientific
reports and application notes, as well as FAQs, to incorporate
customer feedback.
For further information see:
www.radleys.com
 

New Maybridge Organics folder
for synthetic chemists
Maybridge have created an Organics folder containing details of
more than 2,000 organic building block compounds produced by the
Maybridge CombiChem unit. These compounds provide a toolbox for
the organic synthetic chemist complementing the recently launched
Reactive Intermediates range. The Maybridge Organics folder includes
monofunctional compounds, polyfunctional templates and other compound
groups. For reference all products are arranged alphabetically
within their subsections, classified according to functional group.
For further information see:
www.maybridge.com 

Maybridge databases now
available online
Downloadable files of an extensive library
of Maybridge databases has been added to the Maybridge website.
The new files are of the Combinatorial Chemistry, Reactive Intermediates
and HTS databases. These files will be updated on a monthly basis
and are freely available to all visitors to the site in SD files,
PDF files and Excel formats.
For further information see:
www.maybridge.com 

Elkay release Stronger Screw
Capped Micro Tubes
Elkay release stronger screw capped micro tubes,
designed for centrifugation and low temperature storage. Robustly
constructed, these tubes are designed for working with or storing
costly, low volume reagents or biological specimens. Elkay's new
polypropylene micro tubes can withstand low temperature storage
to -190ºC, autoclaving to +121ºC and centrifugation
speeds to 17,000g.
The potential risk of explosion that could occur
due to vacuum pressure build up when thawing samples from frozen,
has been resolved by incorporating a safety gasket in the screw
cap to ensure a leak tight seal especially during the thawing
process. Various tube sizes, 0.5ml, 1.5ml and 2ml are available,
with or without printed graduations, and skirted or non-skirted
footprints. The tubes come in sterile packs with natural coloured
caps attached and in non-sterile packs. Separate caps are available
in nine different colours.
For further information see:
www.elkay-uk.co.uk
 

Radleys introduce a Cooled
Carousel for low temperature parallel synthesis
Radleys Discovery Technologies has extended its range of parallel
synthesis reaction stations with a Cooled Carousel for low temperature
applications to -70°C. Based on the original Carousel design,
the Cooled Carousel fits on a standard stirrer and can simultaneously
perform twelve cooled, inert and stirred reactions for parallel
solution phase or solid supported reagent based synthesis.
The
HDPE 'cooling reservoir' is compatible with a range of manual
freezing mixtures, including dry ice / acetone for efficient cooling
from ambient down to -70°C. The 'cooling reservoir's' incorporates
an insulated foam core which maintains low temperatures for long
periods, whilst protecting the stirrer from freezing. It also
reduces condensation and ice formation on outer surfaces.
For further information see:
www.radleys.com
 
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