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Issue 18

January 2002
Circulation: 6168

The latest information for the Combinatorial Chemistry Community

THIS ISSUE SPONSORED BY ASINEX

ASINEX is recognized as an experienced supplier of unique small organic molecules for pharmaceutical, biotech and agrochemical research and development projects. We currently offer diverse collections of about 300,000 compounds.

ASINEX has sufficient in-house facilities and computational drug design capacities to provide a comprehensive approach to lead discovery and lead optimization.

For detailed information on our products and services please visit
www.asinex.com


WELCOME

Welcome to the monthly Newsletter from CombiChem.net, designed to keep you up to date with what's happening on the combinatorial chemistry scene.

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LATEST NEWS & PRODUCTS

Jan 14 - deCODE genetics to Acquire MediChem Life Sciences

Jan 14 - Matrix Pharmaceutical, Inc. acquired by the Chiron Corporation

Jan 14 - Illumitek Inc. Launches Into Life Sciences Through Strategic Relationship With Viaken Systems

Jan 14 - Genevac DD- 4 & Metz Syn10 on Display at Labautomation 2002

Jan 10 - IBM and Accelrys form global strategics alliance to transform drugs research and development

Jan 9 - Symyx Technologies Announces Discovery Tools Agreement with Lilly

Jan 9 - Structural GenomiX to Collaborate with Aventis on Lead Compound Identification

Jan 9 - Biotage Breaks Ground on New Worldwide Headquarters Facility

Advanced Pharma Algorithms release Advanced Algorithm Builder

Jan 7 - 3-Dimensional Pharmaceuticals Announces DiscoverWorks(R) Drug Discovery Alliance With Johnson & Johnson Pharmaceutical Research & Development

Jan 7 - Tripos Inc. and Pfizer form two software discovery agreements

Jan 3 - Alliance brings chips to Japan

Jan 3 - Collaboration aims at pharmacophores

Jan 3 - Argonaut Announces Major Cost Savings Initiative

Jan 3 - PerkinElmer Announces Sale of Two Product Lines; Divestitures Increase Focus on High-Growth Markets

Dec 18 - ChemNavigator Compound offerings surpass 2.3 Million compounds with the addition of CambridgeSoft's ChemACX reagent database

Dec 18 - Argenta Discovery announces research agreement with GlaxoSmithKline

Dec 17 - Milestone announce their Tea & Synthesis Breakfast Seminar Series

Dec 17 - Perkinelmer Life Sciences establishes new European technical center in Cambridge, U.K.

Dec 14 - Genesis highlights Londons biotech strengths

Dec 12 - Roche and Chugai create new Japanese pharma company

Further News or New Product information


Milestone's EthosSYNTH Microwave Labstation offers you a modular platform to accelerate your combinatorial chemistry, reducing reactions times from hours to minutes, often with higher yields and improved yield purity.

From combinatorial chemistry to parallel synthesis to batch reactions, Milestone offers a comprehensive collection of modular reaction vessels for discovery through development to production.


For detailed information on our products and services please visit Milestone


UPCOMING EVENTS PREVIEW

 

COMBI 2002 - The 4th Annual International Symposium on Combinatorial Approaches for New Materials Discovery
23 - 25th January, 2002, San Diego, CA, USA
Combi 2002 will examine the latest developments in:

Combinatorial and high-throughput methods
Experimental design for parallel libraries and high-throughput screening
Synthesis and discovery of new inorganic materials, catalysts, organic polymers, electronic and photonic materials
Rapid technology
Instrumentation and tools
Information handling and processing

 

LabAutomation 2002
26 - 30, January 2002, Palm Springs, CA, USA

LabAutomation is now in it's sixth year, and provides a forum where creators and users of automation technologies can exchange ideas, interact and form new partnerships. Keeping up with the latest technologies and techniques is a daunting challenge for today's scientist. The Association for Laboratory Automation aims to facilitate this process.

Topics include:
Genomics, Proteomics, High Throughput Screening,
Combinatorial Chemistry, Microfluidics, Emerging Technology
Informatics, Mass Spectrometry, Analytical, ADME - Toxicology, Drug Discovery Case Studies

 

Drug Discovery Japan
28 - 31th January, 2002, Tokyo, Japan
Drug Discovery Japan brings together leading researchers from around the world to discuss their experiences with many aspects of the drug discovery process from bioinformatics, proteomics, target identification and validation, to screening of combinatorial libraries, structure-based drug design, and ADME/Tox studies.

 

Exploiting Molecular Diversity
February 11-12, 2002, San Diego, California, USA

Anyone interested in learning how to develop more effective libraries faster and cheaper, as well as learning from case studies where informed design in conjunction with novel assay development has been successful, should attend this meeting.

Main topics to be covered will be:

  • DRUGLIKE CHARACTERISTICS AND BIOLOGICAL RELEVANCE
  • LIBRARY SCREENING FOR SMALL MOLECULE LEADS
  • RESULTS FROM TARGET-FOCUSED LIBRARIES
  • COMPUTATIONALLY DRIVEN LIBRARY DESIGN TO LEAD DISCOVERY

 

High-Throughput Organic Synthesis
February 13-15, 2002, San Diego, California, USA

This conference will highlight recent novel chemistries and reaction strategies, as well as optimization of reactions for library synthesis. Case examples of resins, linkers, and cleavage methods that make compound synthesis easier, faster, and more practical will be presented with emphasis on quality and high-throughput purification techniques.

Main topics to be covered will be:

  • SOLID-PHASE SYNTHESIS
  • SOLUTION-PHASE SYNTHESIS
  • SPECIFIC EXAMPLES OF NOVEL RESINS, CATALYSTS, AND SCAFFOLDS
  • IMPROVING QUALITY AND PRODUCTIVITY IN CHEMISTRY DEVELOPMENT
  • PURIFICATION AND ANALYSIS

 

Predicting Drug Metabolism
14-15th - February , 2002, Park Hyatt Philadelphia at the Bellevue, Philadelphia, PA

Attend this conference and examine issues such as Predictive Drug Metabolism and Pharmacokinetics: Utility in Accelerating Early Drug Safety Evaluation and Clinical Development, Dramatic developments in the technology of coupling NMR to liquid chromatography (LC/NMR or flow NMR, Qualitative versus quantitative predictions — how best to interpret in vitro metabolism models and Usefulness of in vitro tools for the characterization of UGT enzymes in HLM.

For links to about 25 events taking place in February and March check out THE BEST listing on the net.
To add new events please Email


ONLINE RESOURCES

CombiChem.net also offers these additional resources:

DISCUSSION FORUMS - specialist areas grouped into convenient categories
PATENTS - hand picked, complete with summaries
PUBLICATIONS - books, reviews, abstracts of published papers and more.
JOBS INDEX - for specialist laboratory, engineering or sales/marketing personnel.

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ASSOCIATED NEWSLETTERS

If you found this newsletter of use, you may be interested in signing up to one of our associated free newsletters:

  • HTScreening.net for the High Throughput Screening Community
  • HighThroughputExperimentation.com for Catalysts and Materials Development
  • Lab-on-a-Chip.com for those interested in Miniaturized Technology for Lab Applications
  • PharmacoGenomicsOnline.com for developments in Pharmacogenomics, Genomics and Proteomics

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